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1

Application of computational toxicological approaches in human health risk assessment. I. A tiered surrogate approach

Nina Ching Yi Wang, Q. Jay Zhao, Scott C. Wesselkamper, Jason C. Lambert, Dan Petersen, Janet K. Hess-Wilson

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 579 KB

english, 2012

2

Weak completeness and Abelian semigroups

T. C. Wesselkamper

Journal:

Mathematical Logic Quarterly

Year:

1975

Language:

english

File:

PDF, 167 KB

english, 1975

3

No Abelian Semigroup Operation is Complete

T. C. Wesselkamper

Journal:

Mathematical Logic Quarterly

Year:

1976

Language:

english

File:

PDF, 130 KB

english, 1976

4

The algebraic representation of partial functions

T.C. Wesselkamper

Journal:

Discrete Applied Mathematics

Year:

1979

Language:

english

File:

PDF, 442 KB

english, 1979

5

CD8+ T cells contribute to macrophage accumulation and airspace enlargement following repeated irritant exposure

Michael T. Borchers, Scott C. Wesselkamper, Nathaniel L. Harris, Hitesh Deshmukh, Erin Beckman, Mark Vitucci, Jay W. Tichelaar, George D. Leikauf

Journal:

Experimental and Molecular Pathology

Year:

2007

Language:

english

File:

PDF, 1.10 MB

english, 2007

6

Divided Difference Methods for Galois Switching Functions

Wesselkamper, T.C.

Journal:

IEEE Transactions on Computers

Year:

1978

Language:

english

File:

PDF, 2.06 MB

english, 1978

7

Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments

Maureen A Sartor, Craig R Tomlinson, Scott C Wesselkamper, Siva Sivaganesan, George D Leikauf, Mario Medvedovic

Journal:

BMC Bioinformatics

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

8

Glutathione deficient C57BL/6J mice are not sensitized to ozone-induced lung injury

Elisabet Johansson, Scott C. Wesselkamper, Howard G. Shertzer, George D. Leikauf, Timothy P. Dalton, Ying Chen

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 352 KB

english, 2010

9

Computer Program Schemata and the Processes They Generate

Wesselkamper, T.C.

Journal:

IEEE Transactions on Software Engineering

Year:

1982

Language:

english

File:

PDF, 3.50 MB

english, 1982

10

Quantitative trait analysis of the development of pulmonary tolerance to inhaled zinc oxide in mice

Scott C Wesselkamper, Lung Chi Chen, Terry Gordon

Journal:

Respiratory Research

Year:

2005

Language:

english

File:

PDF, 2.15 MB

english, 2005

11

Chronic Cigarette Smoke Exposure Generates Pathogenic T Cells Capable of Driving COPD-like Disease in Rag2 −/− Mice

Motz, Gregory T., Eppert, Bryan L., Wesselkamper, Scott C., Flury, Jennifer L., Borchers, Michael T.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 1.69 MB

english, 2010

12

Putative Mechanisms of Environmental Chemical-Induced Steatosis

Kaiser, J. P., Lipscomb, J. C., Wesselkamper, S. C.

Journal:

International Journal of Toxicology

Year:

2012

Language:

english

File:

PDF, 481 KB

english, 2012

13

[IEEE Comput. Soc. Press 24th International Symposium on Multiple-Valued Logic (ISMVL'94) - Boston, MA, USA (25-27 May 1994)] Proceedings of 24th International Symposium on Multiple-Valued Logic (ISMVL'94) - Searching for complete functions over E(3) with small radii

Cabrasawan, F.J., Wesselkamper, T.G.

Year:

1994

Language:

english

File:

PDF, 518 KB

english, 1994

14

DURATION-DEPENDENT CYTOPROTECTIVE VERSUS INFLAMMATORY EFFECTS OF LUNG EPITHELIAL FIBROBLAST GROWTH FACTOR-7 EXPRESSION

Tichelaar, Jay W., Wesselkamper, Scott C., Chowdhury, Supurna, Yin, Hulian, Berclaz, Pierre-Yves, Sartor, Maureen A., Leikauf, George D., Whitsett, Jeffrey A.

Journal:

Experimental Lung Research

Year:

2007

Language:

english

File:

PDF, 744 KB

english, 2007

15

[IEEE First IEEE Conference on Evolutionary Computation. IEEE World Congress on Computational Intelligence - Orlando, FL, USA (27-29 June 1994)] Proceedings of the First IEEE Conference on Evolutionary Computation. IEEE World Congress on Computational Intelligence - Genetic algorithm techniques for 3-valued transistor design

Cabrasawan, F.J., Lesniak, J., Wesselkamper, T.C.

Year:

1994

Language:

english

File:

PDF, 404 KB

english, 1994

16

[IEEE Comput. Soc. Press 25th International Symposium on Multiple-Valued Logic - Bloomington, IN, USA (23-25 May 1995)] Proceedings 25th International Symposium on Multiple-Valued Logic - Some new results for multiple-valued genetic algorithms

Wesselkamper, T.C., Danowitz, J.

Year:

1995

Language:

english

File:

PDF, 565 KB

english, 1995

17

Persistence of Lung CD8 T Cell Oligoclonal Expansions upon Smoking Cessation in a Mouse Model of Cigarette Smoke-Induced Emphysema

Motz, G. T., Eppert, B. L., Sun, G., Wesselkamper, S. C., Linke, M. J., Deka, R., Borchers, M. T.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 401 KB

english, 2008

18

Chronic Cigarette Smoke Exposure Primes NK Cell Activation in a Mouse Model of Chronic Obstructive Pulmonary Disease

Motz, G. T., Eppert, B. L., Wortham, B. W., Amos-Kroohs, R. M., Flury, J. L., Wesselkamper, S. C., Borchers, M. T.

Journal:

The Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 602 KB

english, 2010

19

The NKG2D-Activating Receptor Mediates Pulmonary Clearance of Pseudomonas aeruginosa

Borchers, M. T., Harris, N. L., Wesselkamper, S. C., Zhang, S., Chen, Y., Young, L., Lau, G. W.

Journal:

Infection and Immunity

Year:

2006

Language:

english

File:

PDF, 441 KB

english, 2006

20

Development of Pulmonary Tolerance in Mice Exposed to Zinc Oxide Fumes

Wesselkamper, S. C., Chen, L. C., Gordon, T.

Journal:

Toxicological Sciences

Year:

2001

Language:

english

File:

PDF, 299 KB

english, 2001

21

Nonredundant Functions of and T Cells in Acrolein-Induced Pulmonary Pathology

Borchers, M. T., Wesselkamper, S. C., Eppert, B. L., Motz, G. T., Sartor, M. A., Tomlinson, C. R., Medvedovic, M., Tichelaar, J. W.

Journal:

Toxicological Sciences

Year:

2008

Language:

english

File:

PDF, 535 KB

english, 2008

22

Candidate genes controlling pulmonary function in mice: transcript profiling and predicted protein structure

Ganguly, K., Stoeger, T., Wesselkamper, S. C., Reinhard, C., Sartor, M. A., Medvedovic, M., Tomlinson, C. R., Bolle, I., Mason, J. M., Leikauf, G. D., Schulz, H.

Journal:

Physiological Genomics

Year:

2007

Language:

english

File:

PDF, 951 KB

english, 2007

23

Temporal Concordance Between Apical and Transcriptional Points of Departure for Chemical Risk Assessment

Thomas, R. S., Wesselkamper, S. C., Wang, N. C. Y., Zhao, Q. J., Petersen, D. D., Lambert, J. C., Cote, I., Yang, L., Healy, E., Black, M. B., Clewell, H. J., Allen, B. C., Andersen, M. E.

Journal:

Toxicological Sciences

Year:

2013

Language:

english

File:

PDF, 3.02 MB

english, 2013

24

Epigenetic Regulation in Environmental Chemical Carcinogenesis and its Applicability in Human Health Risk Assessment

S. P. Kuppusamy, J. P. Kaiser, S. C. Wesselkamper

Year:

2015

Language:

english

File:

PDF, 285 KB

english, 2015

25

Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment

Thomas, R. S., Clewell, H. J., Allen, B. C., Wesselkamper, S. C., Wang, N. C. Y., Lambert, J. C., Hess-Wilson, J. K., Zhao, Q. J., Andersen, M. E.

Journal:

Toxicological Sciences

Year:

2011

Language:

english

File:

PDF, 665 KB

english, 2011

26

Superoxide dismutase 3, extracellular (SOD3) variants and lung function

Ganguly, K., Depner, M., Fattman, C., Bein, K., Oury, T. D., Wesselkamper, S. C., Borchers, M. T., Schreiber, M., Gao, F., von Mutius, E., Kabesch, M., Leikauf, G. D., Schulz, H.

Journal:

Physiological Genomics

Year:

2009

Language:

english

File:

PDF, 445 KB

english, 2009

27

Genomic Profile of Matrix and Vasculature Remodeling in TGF-α–Induced Pulmonary Fibrosis

Hardie, William D., Korfhagen, Thomas R., Sartor, Maureen A., Prestridge, Adrienne, Medvedovic, Mario, Le Cras, Timothy D., Ikegami, Machiko, Wesselkamper, Scott C., Davidson, Cynthia, Dietsch, Maggie

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

28

Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

Deshmukh, Hitesh S., Case, Lisa M., Wesselkamper, Scott C., Borchers, Michael T., Martin, Linda D., Shertzer, Howard G., Nadel, Jay A., Leikauf, George D.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 328 KB

english, 2005

29

Reciprocal Congenic Lines of Mice Capture the Aliq1 Effect on Acute Lung Injury Survival Time

Prows, Daniel R., Hafertepen, Amanda P., Winterberg, Abby V., Gibbons, William J., Wesselkamper, Scott C., Singer, Jonathan B., Hill, Annie E., Nadeau, Joseph H., Leikauf, George D.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

30

The Role of Metallothionein in the Pathogenesis of Acute Lung Injury

Wesselkamper, Scott C., McDowell, Susan A., Medvedovic, Mario, Dalton, Timothy P., Deshmukh, Hitesh S., Sartor, Maureen A., Case, Lisa M., Henning, Lisa N., Borchers, Michael T., Tomlinson, Craig R.,

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 171 KB

english, 2006

31

Matrix Metalloproteinase-14 Mediates a Phenotypic Shift in the Airways to Increase Mucin Production

Deshmukh, Hitesh S., McLachlan, Anne, Atkinson, Jeffrey J., Hardie, William D., Korfhagen, Thomas R., Dietsch, Maggie, Liu, Yang, Di, Peter Y. P., Wesselkamper, Scott C., Borchers, Michael T., Leikauf

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

32

Dose-Related Protection from Nickel-Induced Lung Injury in Transgenic Mice Expressing Human Transforming Growth Factor- α

Hardie, William D., Prows, Daniel R., Piljan-Gentle, Alyssa, Dunlavy, Michelle R., Wesselkamper, Scott C., Leikauf, George D., Korfhagen, Thomas R.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2002

Language:

english

File:

PDF, 182 KB

english, 2002

33

Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor β

Wesselkamper, Scott C., Case, Lisa M., Henning, Lisa N., Borchers, Michael T., Tichelaar, Jay W., Mason, John M., Dragin, Nadine, Medvedovic, Mario, Sartor, Maureen A., Tomlinson, Craig R., Leikauf, G

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 432 KB

english, 2005

34

Surfactant-Associated Protein B Is Critical to Survival in Nickel-Induced Injury in Mice

Bein, Kiflai, Wesselkamper, Scott C., Liu, Xiangdong, Dietsch, Maggie, Majumder, Nilanjana, Concel, Vincent J., Medvedovic, Mario, Sartor, Maureen A., Henning, Lisa N., Venditto, Carmen, Borchers, Mic

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 431 KB

english, 2009

35

Acrolein-Activated Matrix Metalloproteinase 9 Contributes to Persistent Mucin Production

Deshmukh, Hitesh S., Shaver, Colleen, Case, Lisa M., Dietsch, Maggie, Wesselkamper, Scott C., Hardie, William D., Korfhagen, Thomas R., Corradi, Massimo, Nadel, Jay A., Borchers, Michael T., Leikauf,

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

36

Comparison of two digital hearing instrument fitting strategies

Wesselkamp, Matthias, Margolf-Hackl, Sabine, Kiessling, Jürgen

Journal:

Scandinavian Audiology

Year:

2001

Language:

english

File:

PDF, 245 KB

english, 2001

37

Functional Genomics of Particle-Induced Lung Injury

Leikauf, George D., McDowell, Susan A., Gammon, Kelly, Wesselkamper, Scott C., Bachurski, Cindy J., Alvaro, Puga, Wiest, Jonathan S., Leikauf, John E., Prows, Daniel R.

Journal:

Inhalation Toxicology

Year:

2000

Language:

english

File:

PDF, 6.18 MB

english, 2000

38

Alternative methods in human health risk assessment: Application of a tiered surrogate approach

Lizarraga, L.E., Kaiser, J.P., Lambert, J.C., Wesselkamper, S.C., Zhao, Q.J.

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 85 KB

english, 2015

39

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California - ()] A31. EFFECTS OF CIGARETTE SMOKE ON INFLAMMATORY CELL BIOLOGY - Chronic Cigarette Smoke Exposure Enhances Pulmonary Lymphocyte Sensitivity to Toll-Like Receptor 3, 7 and 9 Stimulation.

Motz, GT, Wesselkamper, SC, Eppert, BL, Borchers, MT

Year:

2009

Language:

english

File:

PDF, 146 KB

english, 2009

40

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California - ()] A50. CYSTIC FIBROSIS BASIC, CLINICAL AND TRANSLATIONAL STUDIES - Superoxide Dismutase 3, Extracellular ( SOD3 ) Variants and Lung Function.

Ganguly, K, Depner, M, Wesselkamper, SC, Schreiber, M, Gao, F, Oury, TD, Mutius, EV, Kabesch, M, Leikauf, GD, Schulz, H

Year:

2009

Language:

english

File:

PDF, 190 KB

english, 2009

41

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California - ()] B32. MUCOSAL IMMUNITY AND AIRWAY EPITHELIA - Sustained NKG2D Ligand Expression in Pulmonary Epithelial Cells Promotes the Development of Emphysema.

Borchers, MT, Wesselkamper, SC, Motz, GT, Eppert, BL

Year:

2009

Language:

english

File:

PDF, 116 KB

english, 2009

42

NKG2D Is Critical for NK Cell Activation in Host Defense against Pseudomonas aeruginosa Respiratory Infection

Wesselkamper, S. C., Eppert, B. L., Motz, G. T., Lau, G. W., Hassett, D. J., Borchers, M. T.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 966 KB

english, 2008

43

Peripheral Neuropathy in an Adolescent Treated With Linezolid

Linam, W Matthew, Wesselkamper, Kristen, Gerber, Michael A.

Journal:

Pediatric Infectious Disease Journal

Year:

2009

Language:

english

File:

PDF, 133 KB

english, 2009

44

Acute Lung Injury

Leikauf, George D., McDowell, Susan A., Wesselkamper, Scott C., Hardie, William D., Leikauf, John E., Korfhagen, Thomas R., Prows, Daniel R.

Journal:

Year:

2002

Language:

english

File:

PDF, 108 KB

english, 2002

45

Application of Gene Set Enrichment Analysis for Identification of Chemically-Induced, Biologically Relevant Transcriptomic Networks and Potential Utilization in Human Health Risk Assessment

Dean, Jeffry L., Jay Zhao, Q., Lambert, Jason C., Hawkins, Belinda S., Thomas, Russell S., Wesselkamper, Scott C.

Journal:

Toxicological Sciences

Year:

2017

Language:

english

File:

PDF, 2.42 MB

english, 2017

46

Pediatric Epilepsy Readmissions: the Who, When, and Why

Vawter-Lee, Marissa, Lutley, Alexandria, Lake, Sharon W., Fledderjohn, Shirley, King, Anna, Horn, Paul S., Wesselkamper, Kristen R.

Journal:

Pediatric Neurology

Year:

2018

File:

PDF, 708 KB

2018

47

A case study on the application of an expert-driven read-across approach in support of quantitative risk assessment of p,p’-dichlorodiphenyldichloroethane

Lizarraga, Lucina E., Dean, Jeffry L., Kaiser, J. Phillip, Wesselkamper, Scott C., Lambert, Jason C., Zhao, Q. Jay

Journal:

Regulatory Toxicology and Pharmacology

Year:

2019

File:

PDF, 919 KB

2019

48

Genetic susceptibility to irritant-induced acute lung injury in mice

Wesselkamper, Scott C., Prows, Daniel R., Biswas, Pratim, Willeke, Klaus, Bingham, Eula, Leikauf, George D.

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2000

Language:

english

File:

PDF, 617 KB

english, 2000

49

Genetic variability in the development of pulmonary tolerance to inhaled pollutants in inbred mice

Wesselkamper, Scott C., Chen, Lung Chi, Kleeberger, Steven R., Gordon, Terry

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2001

Language:

english

File:

PDF, 870 KB

english, 2001

50

A case study on the application of an expert-driven read-across approach in support of quantitative risk assessment of p,p’-dichlorodiphenyldichloroethane

Lizarraga, Lucina E., Dean, Jeffry L., Kaiser, J. Phillip, Wesselkamper, Scott C., Lambert, Jason C., Zhao, Q. Jay

Journal:

Regulatory Toxicology and Pharmacology

Year:

2019

Language:

english

File:

PDF, 919 KB

english, 2019